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From119US$ /night
Check-in
18Jan2026Select date
Check-out
19Jan2026Select date
Rooms and Guests2 Guests, 1 Room
Key details

About the Hotel

4000 Market Street, Hannibal, Missouri, United States, 63401
-
Near the Mark Twain Boyhood Home and Museum
Very good
7.7
7.3
/10
3.3
3.3
/5

Offering spa therapy and a golf course, the 2-star Comfort Inn & Suites - Hannibal is conveniently located, 4.4 km from Mark Twain Boyhood Home and Museum. Highlights at the hotel include a vending machine and a lift, it also offers Wi-Fi in public areas.

Location

The comfortable hotel is situated in the beautiful part of Hannibal, a 10-minute ride from Mark Twain Memorial Lighthouse. Rockcliffe Mansion is 3.5 km from the Comfort Inn & Suites in Hannibal.

This accommodation can be reached in a 39-minute drive from Quincy Regional airport.

Rooms

Some rooms at the smoke-free hotel are appointed with blackout curtains, climate control, and an ironing board along with self-catering options such as a microwave. They are also decorated with an elegant furniture.

Leisure & Business

A heated swimming pool and a fitness area will help you stay healthy. Comfort Inn & Suites - Hannibal also features a photocopy machine and complimentary wireless internet access for those arriving on business.

“I appreciate that the staff seems ready to go the extra mile, as demonstrated by helping with a TV remote. The "usual" breakfast is reportedly plentiful, but some find it disappointingly bland. Convenient parking and effective room-darkening shades are definite advantages.”
Hotel logo
James DavidEditor-in-Chief at Dogfriendly-hotels
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Select your room type

The hotel provides many room choices—family rooms, doubles, and pet-friendly suites—with breakfast, free cancellation, and special offers
Efficiency King Suite Non Smoking
2 persons
28 m² 
1 King-size bed and 1 Sofa bed
King Suite Sofa Bed Non-Smoking
2 persons
28 m² 
1 King-size bed and 1 Sofa bed
Air conditioning
Efficiency King Suite Sofa Bed Non-Smoking
2 persons
28 m² 
1 King-size bed and 1 Sofa bed
Air conditioning
Queen Room Two Queen Beds Non-Smoking
2 persons
28 m² 
2 King Size Beds
Air conditioning
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Rates & availability calendar

See current prices and availability for your chosen dates!

Facilities

Hotels feature amenities designed to keep both you and your pet comfortable

General

  • No smoking on site
  • Internet access
  • Parking
  • Safe deposit box
  • 24-hour reception
  • Express check-in/ -out
  • Pets allowed
  • Rooms/ Facilities for disabled
  • Wheelchair access
  • Lift
  • ATM/Cash machine
  • Vending machines
  • Smoke detectors
  • Fire extinguishers
  • Key card access
  • Key access

Sports & Fitness

  • Fitness centre
  • Cycling
  • Bowling
  • Golf course
  • Fishing

Services

  • Housekeeping
  • Laundry

Dining

  • Picnic area/ Tables

Business

  • Business centre
  • Meeting/ Banquet facilities
  • Fax/Photocopying

Facilities for people with disabilities

  • Toilet for disabled
  • Bathroom for disabled

Spa & Leisure

  • Indoor swimming pool
  • Sun loungers
  • Leisure/ TV room
  • Spa & wellness centre
  • Jacuzzi
  • Shallow end

Room features

  • Air conditioning
  • Heating
  • Sitting area
  • Tea and coffee facilities
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Hotel location

4000 Market Street, Hannibal, Missouri, United States, 63401
Map view
4000 Market Street, Hannibal, Missouri, United States, 63401
Nearby
Oakwood Christian Church
740 m
Prince Avenue Baptist Church
860 m
Church of Christ
950 m
Explore Hannibal
Local Highlights
Top Attractions
Activities
Dining
Entertainment
Huckleberry Park
18 minutes walking
A scenic park with walking trails and picnic areas, perfect for family outings and relaxation in nature.
Mark Twain Boyhood Home and Museum
10-minute drive
The site showcases the life of Samuel Clemens, offering guided tours and exhibits about his childhood.
Rockcliffe Mansion
10-minute drive
A historic mansion offering tours showcasing opulent architecture and rich history from the 1900s.
Sodalis Nature Preserve
35 minutes walking
Offers hiking trails through scenic habitats, ideal for outdoor enthusiasts and birdwatchers.
Outdoor Yoga Classes
10-minute drive
Local studios provide seasonal yoga classes, fostering relaxation in beautiful outdoor settings.
The Brick Oven
5-minute drive
Italian cuisine featuring homemade pasta and wood-fired pizzas in a cozy, rustic environment.
LaBinnah Bistro
10-minute drive
Charming bistro known for creative dishes using local ingredients; popular for vegetarian options.
Famous Bar
5-minute drive
A laid-back bar known for live music events and open mic nights, great for relaxing with friends.
Rivertown Theatre
10-minute drive
Offers a variety of plays and performances, perfect for a cultural night out with family or friends.
Local transport and travel tips
City Centre
Hannibal7 min  ·  4.5 km
Airports
Quincy Regional Airport (UIN)74 min  ·  48.8 km
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Property information and rules
Check-in
from 15:00-23:59
Check-out
until 11 am
Guest Parking
Public parking is possible on site for free.
Internet
High-speed internet access is available in for free.
Breakfast
A buffet breakfast is served and charges are applicable. 
Children & extra beds
There are no extra beds provided in a room.  There are no cots provided in a room. 
Pets
Pets are allowed on request.
Year renovated:
2006
Number of rooms:
74
Former name
Holiday Inn Express Hotel And Suites Hannibal
FAQs
About Comfort Inn & Suites - Hannibal
How far is Comfort Inn & Suites - Hannibal from Quincy Regional Airport?
The hotel is located 50 km from Quincy Regional Airport, approximately a 39-minute drive.
What are the check-in and check-out times at Comfort Inn & Suites - Hannibal?
Check-in is at 15:00 and check-out is by 11:00.
What amenities does Comfort Inn & Suites - Hannibal offer for relaxation?
The hotel features an indoor heated pool, a hot tub, and a spa and wellness centre.
Is there a fitness center available at Comfort Inn & Suites - Hannibal?
Yes, the hotel includes a 24-hour fitness center for guests to use.
What dining options are available at Comfort Inn & Suites - Hannibal?
A complimentary hot breakfast buffet is served daily, and guests can dine at nearby TJ's Supper Club.
Does Comfort Inn & Suites - Hannibal provide free parking?
Public parking is available on-site for free, and a reservation is not required.
What types of room amenities are available at Comfort Inn & Suites - Hannibal?
Rooms include air conditioning, a refrigerator, a flat-screen TV, and coffee/tea makers.
What popular attractions are located near Comfort Inn & Suites - Hannibal?
The hotel is conveniently located near Rockcliffe Mansion (3 km) and the Mark Twain Boyhood Home and Museum (5 km).
Does Comfort Inn & Suites - Hannibal offer business services?
The hotel provides a business center and meeting facilities for business needs.

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