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From119US$ /night
Check-in
04Dec2025Select date
Check-out
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Rooms and Guests2 Guests, 1 Room
Key details

About the Hotel

4000 Market Street, Hannibal, Missouri, United States, 63401
Perfect
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Offering spa therapy and a golf course, the 2-star Comfort Inn & Suites - Hannibal is conveniently located, 4.4 km from Mark Twain Boyhood Home and Museum. Highlights at the hotel include a vending machine and a lift, it also offers Wi-Fi in public areas.

Location

The comfortable hotel is situated in the beautiful part of Hannibal, a 10-minute ride from Mark Twain Memorial Lighthouse. Rockcliffe Mansion is 3.5 km from the Comfort Inn & Suites in Hannibal.

This accommodation can be reached in a 39-minute drive from Quincy Regional airport.

Rooms

Some rooms at the smoke-free hotel are appointed with blackout curtains, climate control, and an ironing board along with self-catering options such as a microwave. They are also decorated with an elegant furniture.

Leisure & Business

A heated swimming pool and a fitness area will help you stay healthy. Comfort Inn & Suites - Hannibal also features a photocopy machine and complimentary wireless internet access for those arriving on business.

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Select your room type

The hotel provides many room choices—family rooms, doubles, and pet-friendly suites—with breakfast, free cancellation, and special offers
Efficiency King Suite Non Smoking
2 persons
28 m² 
1 King-size bed and 1 Sofa bed
King Suite Sofa Bed Non-Smoking
2 persons
28 m² 
1 King-size bed and 1 Sofa bed
Air conditioning
Efficiency King Suite Sofa Bed Non-Smoking
2 persons
28 m² 
1 King-size bed and 1 Sofa bed
Air conditioning
Queen Room Two Queen Beds Non-Smoking
2 persons
28 m² 
2 King Size Beds
Air conditioning
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Rates & availability calendar

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Local transport and travel tips

Overview of transport options available

City Centre
Hannibal 4.5 km
Airports
Quincy Regional (UIN) 48.8 km

Facilities

Hotels feature amenities designed to keep both you and your pet comfortable

General

  • No smoking on site
  • Internet access
  • Free parking
  • Safe deposit box
  • 24-hour reception
  • Express check-in/ -out
  • Pets allowed
  • Rooms/ Facilities for disabled
  • Wheelchair access
  • Lift
  • ATM/Cash machine
  • Vending machines
  • Smoke detectors
  • Fire extinguishers
  • Key card access
  • Key access

Sports & Fitness

  • Fitness centre
  • Cycling
  • Bowling
  • Golf course
  • Fishing

Services

  • Housekeeping
  • Laundry

Dining

  • Picnic area/ Tables

Business

  • Business centre
  • Meeting/ Banquet facilities
  • Fax/Photocopying

Facilities for people with disabilities

  • Toilet for disabled
  • Bathroom for disabled

Spa & Leisure

  • Indoor swimming pool
  • Sun loungers
  • Leisure/ TV room
  • Spa & wellness centre
  • Jacuzzi
  • Shallow end

Room features

  • Air conditioning
  • Heating
  • Sitting area
  • Tea and coffee facilities
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Hotel location

4000 Market Street, Hannibal, Missouri, United States, 63401
Map view
4000 Market Street, Hannibal, Missouri, United States, 63401
Nearby
Oakwood Christian Church
740 m
Prince Avenue Baptist Church
860 m
Church of Christ
950 m
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Property information and rules
Check-in
from 15:00-23:59
Check-out
until 11 am
Guest Parking
Public parking is possible on site for free.
Internet
High-speed internet access is available in for free.
Breakfast
A buffet breakfast is served and charges are applicable. 
Children & extra beds
There are no extra beds provided in a room.  There are no cots provided in a room. 
Pets
Pets are allowed on request.
Year renovated:
2006
Number of rooms:
74
Former name
Holiday Inn Express Hotel And Suites Hannibal

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Check-in
04Dec2025Select date
Check-out
05Dec2025Select date
Rooms and Guests2 Guests, 1 Room